Serene
stay serene ~ a practice of return
serene sleep · 01

sleep deep.
wake renewed.

4.9 · 284 reviews

a nightly ritual of peptides, glycine, and adaptogens formulated to deepen sleep architecture, so you don't just fall asleep, you stay there.

tart, deep, floral
1
  • free shipping over $50
  • better night sleep guarantee
  • third-party tested · made in usa
02 — what's inside

seven ingredients,
no filler.

01

PeptiSleep™

250mg
Nuritas, rice bran (AI-discovered peptide)

suppresses cortisol via adrenal cortex and orexin receptor modulation. clinically shown to help you fall asleep faster and increase deep sleep, without dependency.

02

magnesium Albion®

200mg
Albion Minerals (chelated form)

highest-bioavailability magnesium form. supports nervous system regulation, muscle relaxation, and sleep architecture.

03

glycine

3,000mg
amino acid (fermentation-derived)

lowers core body temperature to signal sleep onset. improves sleep quality and next-day cognitive performance.

04

CherryPURE®

200mg
Shoreline Fruit (Montmorency tart cherry)

natural melatonin precursor and antioxidant. supports sleep duration and reduces exercise-induced inflammation.

05

L-Theanine AlphaWave®

200mg
AlphaWave® (green tea extract)

promotes alpha brain-wave activity. creates calm without drowsiness and works synergistically with PeptiSleep.

06

Relissa™ lemon balm

200mg
Relissa™ (Melissa officinalis)

clinically studied for reducing anxiety and improving sleep quality. works on GABA receptors without sedation.

07

chamomile

100mg
botanical (Matricaria chamomilla)

traditional nervine herb. supports relaxation and digestive calm as part of an evening wind-down routine.

all ingredients manufactured in a GMP-certified, NSF-accredited facility in Valencia, CA. no artificial colors, fillers, or proprietary blends.

03 — how it works

not a sedative.
an architecture.

01

onset

glycine drops core body temperature, the body's sleep signal. lemon balm softens anxious rumination.

02

depth

peptisleep™ and magnesium extend slow-wave sleep, the repair phase most adults are missing.

03

wake

no antihistamines, no melatonin overload. you wake with your own rhythm intact.

+47min
additional deep sleep per night (n=84 trial, 14 nights)
92%
reported waking more rested (self-report, 30 day panel)
0
morning grogginess reported in trial
04 — the ritual

four minutes.
every night.

  1. 01

    dim the room

    lower lights an hour before bed. your circadian rhythm is listening.

  2. 02

    stir one scoop

    into six ounces of cool water. not carbonated, not warm.

  3. 03

    let it settle

    sip slowly. the ritual is part of the formula.

  4. 04

    return

    to bed, to breath, to yourself. the rest takes care of itself.

05 — what people say
4.9· based on 284 verified reviews

rest, written down.

first sleep supplement that didn't leave me foggy. i wake up actually rested.
maya k. · nyc
the honey lavender is unreasonably good. i look forward to the ritual.
jonah r. · sf
i've tried everything. this is the only one i've repurchased.
priya s. · austin
works well. wish the tub were larger; i'm already a month in.
dan v. · brooklyn
06 — questions

good questions.
honest answers.

30 to 60 minutes before bed. stir one scoop into cool water. let it settle, let yourself settle.

no. serene sleep is 100% melatonin-free. unlike most sleep supplements, it works by reducing cortisol (the stress hormone that keeps you awake) rather than introducing external melatonin, which can disrupt your body's own production over time.

no. peptisleep™ suppresses evening cortisol but does not interfere with morning cortisol, the signal that wakes you up naturally. clinical participants reported improved next-day energy and clarity.

no. none of the ingredients in serene sleep create dependency. you can use it nightly as part of your routine or on an as-needed basis.

peptisleep™ was identified by nuritas using their proprietary magnifier AI platform, which screens plant proteins at a molecular level to find bioactive peptides with specific health functions, a process that would take decades with traditional research. it's backed by published clinical trials.

yes. berry hibiscus and honey lavender are formulated with natural flavor systems. no artificial sweeteners, dyes, or synthetic flavoring agents.

berry hibiscus reads bright and tart, a good call if you like kombucha or hibiscus tea. honey lavender is softer and warmer, more like a nightcap.

in valencia, ca, at a GMP-certified, NSF-accredited facility that also manufactures for brands sold at GNC, whole foods, and walmart. products are also health canada and EU compliant.

save 15% on every tub. change your cadence any time. pause, skip, or cancel from your account. no calls, no forms.